EVALUATION OF FERTILITY AND SERUM
FSH, LH, TESTOSTERON LEVELS
IN TESTICULAR CANCER PATIENTS
Article published in Urologia Polska 2000/53/1.
authors
-
Tomasz Demkow 1, Ricardo Faundez 2, Jacek Kamoda 3, Tomasz Kalinowski 1
- 1 Klinika Nowotworów Układu Moczowego Instytutu Onkologii w Warszawie
p.o. Kierownika Kliniki: dr n. med. T. Demkow
2 Katedra Chorób Wewnętrznych z Kliniką Wydziału Weterynaryjnego SGGW w Warszawie
Kierownik Katedry: prof. dr hab. E. Sitarska
3 Klinika Medyczna Consilium
Kierownik: dr n. med. J. Korzycki
keywords
-
testis neoplasm chemotherapy semen hormones
summary
- Introduction. In the last 20 years treatment results of testicular cancer patients
- has been improved. At the present time up to 90% of the patients are cured.
- Following successful treatment young men want to assess their fertility and
- possibility to have children.
- Objective. The impact of the standard chemotherapy in testicular cancer patients
- on ejaculate volume, sperm count, motility, percentage of abnormal sperm cell,
- vitality, serum FSH, LH, testosteron levels and volume of remaining testicle
- has been assessed.
- Patients and method. In 33 patients with testicular cancer sperm and serum
- FSH, LH, testosteron before and after 3,6,12,18,24 months after chemotherapy
- has been analysed.
- Results. Before chemotherapy in 7 of 33 patients sperm analysis revealed no
- abnormalities according to WHO criteria. 3,12, 24 months after chemotherapy
- sperm analysis revealed no abnormalities respectively in 1 patient, 6 patients
- and 7 patients.
- Conclusions: 1. Most of the testicular cancer patients have impaired
- spermatogenesis before any treatment.
- 2. The most impaired spermatogenesis has been assessed just after
- chemotherapy- .
- 3. In some testicular cancer patients sperm parameters normalize gradually
- after completing chemotherapy.
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