authors
-
Zbigniew Tański, Adam Janiak
- Oddział Urologiczny Wojewódzkiego Szpitala Zespolonego w Ostrołęce
Ordynator Oddziału: lek. med. E. Pogodski
Zakład Patomorfologii Wojewódzkiego Szpitala Zespolonego w Ostrołęce
Kierownik Zakładu: dr n. med. A. Janiak
keywords
-
bladder thyroid hormones low T3 syndrome
summary
- Objective. The low T3 syndrome is often observed at patients with serious
- chronic diseases. The aim of the study was the estimation of changes in serum
- concentrations of the thyroid hormones at patients with genito-urinary tract
- diseases.
- Material and methods. The study was done at 33 patients: 7 women and 26
- men. Among them were: 10 pts with cystolithiasis, 11 pts with bladder
- carcinoma, 1 pts with bladder papilloma, 11 pts with cystitis. In all patients
- following examinations were done: ultrasonography of the abdomen, IVP
- biochemical examinations: serum concentration of T3,T4 creatinine, BUN,
- proteinogram. EIA-ABBOT method was used to estimate T3 and T4 serum
- concentrations.
- Results. The following results of serum T3 concentrations were observed: at
- bladder stone patients from 1.0 to 2.6 nmol/1, medium 1.71 ? 0.4 nmol/1, at
- bladder cancer patients from 1.0 to 2.0 nmol/1, medium 1.6 ? 0.3 nmol/1, at
- patients with cystitis from 1.2 to 3.0 nmol/1, medium 1.7 ? 0.5 nmol/1. The
- serum concentrations of creatinine and proteins were normal.
- Conclusions. The low T3 syndrome was not observed at patients with genito-
- urinary tract diseases such as bladder stone diseases, cystitis and bladder
- carcinoma. At 8 pts after surgical treatment without complications the serum
- T3 concentrations were normal too. At 3 patients with serum T3 postoperative
- infection the serum T3 concentrations were significantly lowered.
references
- [1] Ceremużyński, L.: Hormonal and metabolic reactions evoked by acute myocar-
- dial infarction. Circ. Res. 1981, 48, 767-770.
- [2] Dutkiewicz, S., Kałczak, M.: Quantitative-comparative histology of prostatic
- adenomas in medically and surgically treated patients. Int. Urol. Nephrol. 1994, 26,
- 1-5.
- [3] Epstein, F. H.: The molecular basis of thyroid hormone action. Br. Med. J. 1994,
- 331, 847-851.
- [4] Holland, F. W. i wsp.: Cardiopulmonary Bypass and Thyroid Function: A Eu-
- thyroid Sick Syndrome. Soc. Thor. Surg. 1991, 46-49.
- [5] Kohrle, J.: Thyroid hormone deiodination in target tissues - a regulator role for
- the tracę element selenium? Exp. Clin. Endocrinol. 1994,102, 63-66.
- [6] Kohrle, J. i wsp.: Type 15'-deiodinase - a marker for differentiated thyroid car-
- cinoma? Exp. Clin. Endocrinol. 1993,101, 60-64.
- [7] Koller, J. i wsp.: Thyroid hormones and their impact on the hemodynamic and
- metabolic stability of organ donors and on kidnay graft function after transplanta-
- tion. Transplant. Proc. 1990, 22, 355-359.
- [8] Lee, P. C. i wsp.: Thyroid hormone responses in the early kidney transplants.
- Transplant. Proc. 1994, 26, 2184-2191.
- [9] Nauman, A.: Tarczyca i mechanizmy regulujące wydzielanie aktywnego hormo-
- nu. Endokrynol. Pol. 1993, 44,109-112.
- [10] Nauman, A. i w sp.: Aktywność T4 5'-dejodynazy w raku jasnokomórkowym nerki.
- Dzień Urologiczny Polskiego Towarzystwa Urologicznego, Łódź, 27 wrze-
- śnia 1991. Pamiętnik PTU 1991, 5-9.
- [11] Nauman, A. i wsp.: Serum thyroid hormones concentrations in patients with
- kidney cancer before and after unilateral nephrectomy. Eur. J. Endocrinol. 1995,5,
- 2-6.
- [12] Silva, J. J. E. i wsp.: Evidence for two tissues - specific pathways for in vivo
- thyroxin 5'-deiodination in the rat. J. Clin. Invest. 1982, 69,1176-1179.
- [13] Vaziri, N. D.: Endocrinological conseąuences of the nephrotic syndrome. Am. J.
- Nephrol. 1993,13, 360-364.
- [14] Wartof sky, L.: The low T3or sick euthyroid syndrome: update 1994. Endocr. Soc.
- 1994, 3, 248-252.
|