PTU - Polskie Towarzystwo Urologiczne
list of articles:

The effect of the administration recombinat activated factor Vila (rFVIIa) in intraoperative bleeding in patient undergoing kidney tumorectomy
Article published in Urologia Polska 2001/54/4.


Grażyna Michalska-Krzanowska, Elżbieta Stasiak-Pikuła, Renata Sajdak
Oddział Anestezjologii, Reanimacji i Intensywnej Terapii z Pododdziałem Ostrych Zatruć, Samodzielny Publiczny
Szpital Kliniczny nr 2 w Szczecinie
Kierownik: dr n. med. Grażyna Michalska-Krzanowska


kidney, RCC recombinant activated factor VII, hemostasis, perioperative bleeding


Severe uncontrolled perioperative bleedings very serious medical problem during surgical and intensive treatment. NovoSeven (recombinant activated factor VII - rFVIIa, Novo Nordisk, Denmark) is a new generation drug, received mean of genetic of DNA. Autors Present own experiences in use of NovoSeven in 33-year old man in whom, standard anlihaemor-rhagic treatment not effective. The patient received one dose of NovoSeven. Short time after administration of the drug: reduction in bleeding, normalization of hemostasis parameters and hemodinamics stabilization of the patient were reported. This case confirmes good effect of NovoSeven in rapid treatment the perioperative severe bleedings. The use of NovoSeven may reduce blood transfusion, immunnologic and infectious posttranfusion complications.


  1. 1. Boxer RJ, Frtzsche P, Skinner DG, Kaufman JJ, Belt E, Smith R, Goodwin W E: Replacement of the ureter by small intestine: clinical application and results of the ileal ureter in 89 patients. J Urol 1979,121,728-731.
  2. 2. McDougal WS: Metabolic complications of urinary intestinal diversion. J Urol 1992,147,1199-1208.
  3. 3. Rampal M, Rossi D, Coulange C, Bentolila E, Masson J, Vail-lanl JL: Ureteric replacament by a reduced calibre ileal graf. Progress in Urology, 1991,1,28-36.


(i raty na Michalska -Krzanowska ul. Powstańców Wielkopolskich 72
70-111 Szczecin
tel/fax: (0-91) 466 11 44