PTU - Polskie Towarzystwo Urologiczne
list of articles:

The assessment of vasculo-stromal coefficient in patients suffering from BPH and prostate cancer using TRUS with power doppier and 3D options
Article published in Urologia Polska 2001/54/1.


Zygmunt Dobrowolski, Janusz Jaszczyński, Tomasz Drewniak, Wojciech Habrat
Katedra i Klinika Urologii Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie Kierownik Kliniki: drhab. med. Zygmunt Dobrowolski


prostate, BPH, cancer, transrectal ultrasonography, 3D, power doppler


Objectives. The aim of the study was the assessment of vascularization of prostate in group of patients suffering from BPH and prostate cancer (CaP) and then the assessment of vasculo-stromal coefficient in peripheral and transitional zone of prostate.
Methods. The equipment used for the study was as follows: ultrasond equipment B&K 2002 Panther ADI with 3D reconstruction and the rectal linear double plane probe 7.5 MHz with power doppler option. The vasculo-stromal coefficient was defined as the ratio of blood vessels surface using power doppler and specially defined surface section of prostate using 3D reconstruction software options. 3D power doppler images were obtained before and after intravenous administration of Levovist. 39 patients with BPH and 14 with CaP were examined. The control group consisted of 10 young men.
Results. 1. The vasculo-slromal coefficient was highest in patients with BPH, average than in those with CaP, and lowest in control grup, 2. Administration of Lcvovist enhanced 5 times visualization of blood vessels in power doppler option. Visualization of blood vessels in power doppler option was enhanced 5 times after Lcvovist administration.


  1. / // Aaminiak R. (i., Bcclage H. P., de la Roselte J. J., at al.; Contrast angiosonography: o technology to improve Doppler ultrasoundexamination Oj\\\'prostate. Eur. Urol. 199°, 35.9-20.
  2. /.\\\'/ Aaminiak R.Ci.. Bcclage H. P.,de la Rosctle.1. J., a(at: Transrectal ultrasound of the prostate: innovations and future applications. J.Urol. 1998,159.1568-1579.
  3. 13] Bogers H. A.. Scdclaar M. P. J., Dcbruyne F. M. J.: Contrast-enhanced three-dimensional power doppler angiography of human prostate: correlation with biopsy outcome. Urology 1999, 54,97-104.
  4. [4] Bree R. L.; Therole o/color Doppler and staging biopsies in prostate amcerdetection. Urology 1997,49(3ASuppl.),31-34.
  5. [5] Fensler A.. Leed Sherebrin. S., ct at: Tltree-dimensional ultrasound imaging of the vasculature. Ultrasonic 1998.36.629-633.
  6. [6] Ismail M, T.. Petersen R. O.. Alexander A. A., et at: Color doppler imaging in predicting the biologic behavior of prostate cancer. Urology 1997.50.906-912.
  7. [7] Kirby R. S.: Pre-lreatment staging of prostate cancer: recent advances and future prospects. Prostate Cancer Prostatic Dis. 1997. I. 2-10.
  8. [8] Lovoipicrre A. M.. Snow R. M.. Frydenbers M., et a!.. Prostatic cancer: role of color Doppler imaging in transrectal sonography. Roentg. 1998. 171, 205-210.
  9. [9] Ragdc II.. Kenny G. M., Murphy G. P.. et at: Transrectal ultrasound microbubble contrast angiography of the prostate. Prostate 1997, 32. 270-283.
  10. [10} Watanabe, M.. Color doppler enhancement with contrast agents for detection of prostatic cancer. Nippon Rinsh 1998. 56, 1040-1044.


ygmunt Dobrowolski
Klinika Urologii CM UJ
ul. Grzegórzecka 18
31-531 Kraków