ESTIMATION OF EFFICIANCY OF PDD EXAMINATION IN PATIENTS WITH SUPERFICIAL BLADDER CANCER
Article published in Urologia Polska 2000/53/1.

authors

Zygmunt Dobrowolski ¹, Janusz Jaszczyński ¹, Leszek Woliński ¹, Wojciech Habrat ², Bolesław Papla ³

¹ Katedra i Klinika Urologii C. M. U. J. w Krakowie
Kierownik: dr hab. med. Z. Dobrowolski
² Szpital Kolejowy w Krakowie
Ordynator: dr J. Malczyk
³ Zakład Patomorfologii C. M. U. J.
Kierownik: prof. dr hab. med. J. Stachura

keywords

bladder carcinoma 5 ALA early diagnosis

summary

Introduction. Bladder cancer takes the 6-place of cancer freąuency in the world.

Cystosscopy turns to be the basic diagnostic method. However smali lesions

may be overlooked due to simillar apparence to normal mucosa.

Objective. Estimation of efficiency of PDD examination in diagnosis of the

superficial bladder cancer.

Material and method. Storz generator and xenon lamp was used to

photodynamic cystoscopy with violet light. 5-ALA was introduced to thebladder

two hours before cystoscopy to induce the intracellular acommodation of the

endogenic protoporphirins which is of fluorescent ability. PDD was performed

in 36 patients with superficial bladder cancer from 34 to 82 years of age (28

men and 8 women).

Results. All lesions which were seen in normal lith cystoscopy turned to be red

in PDD.

Conclusions. PDD makesthe possibility for another neoplasmatic lesions to be

noticed which normally could not be seen in the routine cystoscopy. PDD is

more precise diagnostic method particulary in superficial bladder cancer. This

method with using 20-times enlargement camera may improve the rate of ca in

situ diagnosis. The identification of ca in situ may rerduce the number of blind

biopsy Species becouse the suspected places could be identified more precisly.

references