PTU - Polskie Towarzystwo Urologiczne
list of articles:

The result of treatment of 109 childern with nephroblastoma after pre-operative chemotherapy.
Article published in Urologia Polska 1996/49/2.

authors

Krystyna Sawicz-Birkowska, Jerzy Czernik
z Katedry i Kliniki Chirurgii Pediatrycznej AM we Wrocławiu.
Kierownik Kliniki: prof. dr hab. Jerzy Czernik.

keywords

kidney nephroblastoma in childern Chemiotherapy results of treatment.

summary

The authors present the results of treatment of 109 children with nephroblastoma
treated according the schedules of SIOP Nephroblastoma Committee No 6 andNo 9.
In the 51 patients treated according schedules of SIOP No 6 3 years DFS for whole
group was 74% in 58 patients treated according to SIOP No 9 (schedule with 4-wceks
preopcrative chemotherapy) 3 years DFS for whole group was 83%. The advantagcs of
a prcopcrative treatment in tenns of surgical tumor rupture and stage distributions has
been proven.

references

  1. 1. Beckwith J.B., Palmer N.: Histopathology and prognosis of Wilms tumour. The re-
  2. sults of National Wilms Tumour Study. Cancer 1978, 41, 1937-1948.
  3. 2. Beckwith J.B.: Wilms tumour and other renal tumors of childhood. Human Pathol.,
  4. 1983, 14, 481-492.
  5. 3. Grundy R, Breslow N., Green DM. et al.: Prognostic factors for children with receu-
  6. rent Wilms tumor: Results from the Second and Third National Wilms Tumor Study
  7. (NWTS 2 and 3). J. Clin. Oncol., 1989, 7, 638-647.
  8. 4. Kogan S.J., Martins II, Santorineau M. el dl.: Successful treatment of renal vein and
  9. vevena cava extension of nephroblastoma by preoperative chemotherapy. J. Urol.,
  10. 1986, 136, 312-320.
  11. 5. de Kraker J., Lemerle J., Voute P el al: Wilms tumor with pulmonary metastases at
  12. diagnosis. The significance of primary chemotherapy. J. Clin. Oncol., 1990, 8, 1187-
  13. 1190.
  14. 6. Kajtar PG., Pinter A.: Progress in treatment of Wilms tumor. Amer. J. Ped. Hemat./
  15. Oncol., 1988, 10, 237-238.
  16. 7. LemerleJ., Voute P.A., Tournade M.F. et al.: Effectivcness of preoperative chemothe-
  17. rapy in Wilms tumor Results of an International Society of Pediatric Oncology. J.
  18. Clin. Oncol., 1983, 1, 604-609.
  19. 8. Sawicz-Birkowska K.: Udział chemioterapii przedoperacyjnej w leczeniu nerczaka u
  20. dzieci. Probl. Chir. Dziec, 1993, Supl. VIII Zjazd Naukowy Pol. Tow. Chir. Dziec,
  21. Wyd. PZWL Warszawa, red. Z. Kaliciński, 311-316.
  22. 9. Sawicz-Birkowska K., Radwańska U., Czernik J. et al.: Wstępna ocena wyników le-
  23. czenia nerczaka wg schematu 01-92 Pol. Grupy Pediatrycznej leczenia Guzów Li-
  24. tych. Przegl. Ped., 1995, 25, Supl. 3, 257-262.
  25. 10. Tournade M.F., de KrakerJ., LemerleJ., Carli M., et al.: Preoperative chemotherapy
  26. of patients over 6 month of age with a nephroblastoma. A report of the SIOP Wilms
  27. Tumor Trials and Studies. Med. Ped. Oncol., 1994, 23, 171.
  28. 11. Tournade M.F., Com-Nougue C, Voute P.A., et al.: Results of 6th International So-
  29. ciety of Pediatric Oncology Wilms Tumor Trial and Study. J. Clin. Oncol., 1993, 11,
  30. 1014-20.
  31. 12. Zuppan C. W., Beckwith J.B., Weeks D.A., et al.: The effect of preoperative chemothe-
  32. rapy on the histologic features of Wilms tumor. Cancer 1991, 68, 385-394.
  33. 13. Delemarre F.M.: The new SIOP classification of renal tumor of childhood., Med.
  34. Ped. Oncol., 1996, 26, 145-146.