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THE INFLUENCE OF EXTRACORPOREAL SHOCK WAVE LITHOTRIPSY (ESWL) ON THE GENERATION AND SECRETION OF ENDOTHEL1N (ET) IN CH1LDERN.
Article published in Urologia Polska 1995/48/2.

authors

Tomasz Ferenz, Artur A. Antoniewicz, Andrzej Borówka, Leszek Pęczek, Janusz Judycki, Andrzej Borkowski
Z Katedry i Kliniki Urologii A.M. w Warszawie
Kierownik Katedry i Kliniki urologii A.M. w Warszawie
Prof. dr hab. n.med. Andrzej Borkowski
Z Instytutu Transplantologii A.M. w Warszawie
Kierownik Instytutu Transplantologii
Prof. dr hab. n. med. Mieczysław Lau

summary

ESWL, now an appraved method of urolithiasis treatment, is not free of unfavorable adver-
se reactions and complications. There are data available, suggesting, that morbidity of hyper-
tension in ESWL treated patients is twice as high as in non treated population. Endothelin (ET)
is a potent vasoconstricting factor, involved in pathogenesis of hypertension. This prospective
study was aimed to determine the influence of renal tissue trauma in children due to ESWL on
ET blood and urine secretion. In 9 treated children, the ESWL treatment caused gradual, stati-
sticly significant, increase in urine ET levels in children followed up 3 months after the proce-
dure. This increase is not accompanied by statistically significant rise in ET serum levels nor
by increased blood pressure

references

  1. 1. Borówka A., Krzeski T., Judycki T., Górecki R.: Kruszenie kamieni nerkowych i moczowodo-
  2. wych falami wstrz±sowymi wyzwalanymi pozaustrojowo - ESWL. Postępy Nauk Medycznych, 1989,
  3. nr 3, ] 25. ? 2. Ołpiński M., Borówka A., Krzeski T., Judycki J.: ESWL u dzieci. Urol. Pol, 1992,
  4. 45, 2, 87. ? 3. KallerhoffM., Mueller-Siegel K, Verwiebe R., Weber M. H., WassmannK., Blech
  5. M., Scheler F., Ringer! R. H.: Lokalisation und Ausmass einer Gewebeschaedigung durch die extra-
  6. corporale Lithotripsie (ESWL). Urologe [A], 1991, 30, 85. ? 4. Assimos D. C, Boyce W. H, Full
  7. E. C, EspelcmdM. A., Holmes R. P., Harrison LH, KroovandR. L, McCullough D. L: Selective
  8. ekvation of urinary enzyme levels after extracorporeal shock wave lithotripsy. J. Urol., 1989, 142,
  9. 1989, 142, 687 ? 5. Strohmaier W. L, Bichler K. K, Deeljen P., Kleinknecht S., Pedro M., Wilbert D. M:
  10. Damaaing effects of high energy shock waves on cultured Madin Darby Canine Kidney (MDCK)
  11. cells. Urol. Res., 1990, 18, 255. ? 6. Haupt G., Haupt A., Donovan J. M., Drach G. W., Chaussy
  12. Ch.: Short-term changes of laboratory values after extracorporeal shock wave lithotripsy: a compa-
  13. rative study. J. Urol., 1989, 142, 259. ? 7. Montgomeiy B. S. L, Cole R. S., Palfrey E. L. K,
  14. Shuttleworth K. E. D. \ Does extracorporeal shock wave lithotripsy cause hypertension? Brit. J. Urol.,
  15. 1989. 64, 567. ? 8. Kort V., Badr K. F.: Biological actions and pathophysiologic significance of
  16. endothelin in the kidney. Kidney Intern., 1991, 40, 1. ? 9. Eiam-OngS., Hilden S. A., King A. J.,
  17. Johns C. A., Madias N. E. \ Endothelin stimulates the Na+/H+ and Na+/ HCO3- transporters in
  18. rabbit renal cortex. Kidney Intern., 1992, 42, 18. ?10. Luscher T. F., BockH. A., Yang Z, Diede-
  19. nch D.: Endothelium-derived relaxing and contracting factors: perspectives in nephrology. Kidney
  20. Intern., 1991, 39, 575. ? 11. Vane J. R., Anggard E. E., Botting R. M: Regulatory functions of the
  21. sascular endothelium. New England J. Med., 1990, 323, 1, 27. ? 12. Ando K, Hirata Y., Takei Y.,
  22. Kiiwakami M., Marumo F.: Endothelin-1-like immunoreactivity in human urine. Nephron, 1991,
  23. 57, 36. ? 13. Strohmaier W. L., Carl A., Wilbert D. M., Bichler K. H.: Einfluss der extracorporalen
  24. Stosswellenlithotripsie (ESWL) auf Renin ind Endothelinspiegel beim Mensehen. Urologe (A) Sup-
  25. plement, 1993, 2, 38.