PTU - Polskie Towarzystwo Urologiczne
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Article published in Urologia Polska 1988/41/1.


Jan Szymanowski, Zofia Kasprzycka, Maria Barbara Gabryelewicz, Ewa Koźmińska
Z Oddziału Urologii Szpitala Bielańskiego w Warszawie
Ordynator: dr n. med. J. Szymanowski
Z Zakładu Diagnostyki Patomorfologiczne] CMKP w Warszawie Kierownik: prof. dr hab. med. M. Kobuszewska-Faryna


In the renal carcinoma there may also be some changes within the adrenal gland adjoining the focus of the neoplasm, therefore radical nephrectomy should be combined with adrenalectomy.
A group of 98 patients having had radical nephrectomy because of the neph­roma has been examined. In 19 of them (19,38%) microscopic analysis revealed a disease process in the removed adrenal gland. In 12 patients (12,24%) the chan­ges were caused by the renal carcinoma (in 7 cases they were metastasis and in five ? direct malignant infiltration). In the remaining seven patients the chan­ges were found to be mild. Metastasis to the other adrenal gland was the cause of death in the post-operative process in as many as thres patients.
The conclusions is that the radical nephrectomy in patients with renal car­cinoma one should also remove the adrenal gland. Before the operation it is ad-visable to perform dose examinations of the adrenal glands, if possible by means of Computer tomography, ultrasonography, arteriography, and it is necessary to state the level of sterids in the serum and urine.


  1. 1. Chatelain C: Renal tumors: Proceedings of the First International Sym­posium on Kidney Tumors. A. R. Liss. Inc., New York, 1982, 475. ? 2. Fox M., Grant J. B. F., Grainger R. G.: Bilateral adrenal metastases from renal carcinoma treated surgically with Prolonged survival. Brit. J. Urol., 1986, 58, 5, 561. ? 3. Hellsten S., Berge T., Linell F.: Clinically unrecognized renal carcinoma: aspects of tumor morphology, lymphatic and haematogenous metastatic spread. Brit. J. Urol., 1983, 55, 166. ? 4. Kasperlik-Załuska A., Nielubowicz J., Migdalska B., Ku-jawa-Wilamowska J., Wilczyńska J.: Skojarzenie nadczynności kory nadnerczy z rakiem nerki. Nowotwory, 1980, 30, 2, 195. ? 5. Marshall F. F.: Editorial comment. J. Urol., 1986, 135, 3, 455. ? 6. Merrin C. E.: Current operative urology. Harper -Row, Philadelphia, 1984, 36. ? 7. Palmer J. M.: Current operative urology. Harper ? Row, Philadelphia, 1984, 72. ? 8. Parker T. G., Sommers S. C: Adrenal cortical hyperplasia acoompanying cancer. Arch. Surg., 1956, 72, 495. ? 9. Robey E. L., Schelhammer P. F.: The adrenal gland and renal cell carcinoma: is ipsilateral adrenalectomy a necessary component of radical nephrectomy? J. Urol., 1986, 135, 3, 453. ? 10. Robson C. J., Churchill B. M., Anderson W.: The results of radical nephrectomy for renal cell carcinoma. J. Urol., 1969, 101, 2, 297.
  2. 11. Whisenand J. M., Kostas D., Sommers S. C: Some host factors in the de-velopment of renal cell carcinoma. West. J. Med., 1962, 70, 284.