The result of treatment of 109 childern with nephroblastoma
after pre-operative chemotherapy.
Article published in Urologia Polska 1996/49/2.
authors
-
Krystyna Sawicz-Birkowska, Jerzy Czernik
- z Katedry i Kliniki Chirurgii Pediatrycznej AM we Wrocławiu.
Kierownik Kliniki: prof. dr hab. Jerzy Czernik.
keywords
-
kidney nephroblastoma in childern Chemiotherapy results of treatment.
summary
- The authors present the results of treatment of 109 children with nephroblastoma
- treated according the schedules of SIOP Nephroblastoma Committee No 6 andNo 9.
- In the 51 patients treated according schedules of SIOP No 6 3 years DFS for whole
- group was 74% in 58 patients treated according to SIOP No 9 (schedule with 4-wceks
- preopcrative chemotherapy) 3 years DFS for whole group was 83%. The advantagcs of
- a prcopcrative treatment in tenns of surgical tumor rupture and stage distributions has
- been proven.
references
- 1. Beckwith J.B., Palmer N.: Histopathology and prognosis of Wilms tumour. The re-
- sults of National Wilms Tumour Study. Cancer 1978, 41, 1937-1948.
- 2. Beckwith J.B.: Wilms tumour and other renal tumors of childhood. Human Pathol.,
- 1983, 14, 481-492.
- 3. Grundy R, Breslow N., Green DM. et al.: Prognostic factors for children with receu-
- rent Wilms tumor: Results from the Second and Third National Wilms Tumor Study
- (NWTS 2 and 3). J. Clin. Oncol., 1989, 7, 638-647.
- 4. Kogan S.J., Martins II, Santorineau M. el dl.: Successful treatment of renal vein and
- vevena cava extension of nephroblastoma by preoperative chemotherapy. J. Urol.,
- 1986, 136, 312-320.
- 5. de Kraker J., Lemerle J., Voute P el al: Wilms tumor with pulmonary metastases at
- diagnosis. The significance of primary chemotherapy. J. Clin. Oncol., 1990, 8, 1187-
- 1190.
- 6. Kajtar PG., Pinter A.: Progress in treatment of Wilms tumor. Amer. J. Ped. Hemat./
- Oncol., 1988, 10, 237-238.
- 7. LemerleJ., Voute P.A., Tournade M.F. et al.: Effectivcness of preoperative chemothe-
- rapy in Wilms tumor Results of an International Society of Pediatric Oncology. J.
- Clin. Oncol., 1983, 1, 604-609.
- 8. Sawicz-Birkowska K.: Udział chemioterapii przedoperacyjnej w leczeniu nerczaka u
- dzieci. Probl. Chir. Dziec, 1993, Supl. VIII Zjazd Naukowy Pol. Tow. Chir. Dziec,
- Wyd. PZWL Warszawa, red. Z. Kaliciński, 311-316.
- 9. Sawicz-Birkowska K., Radwańska U., Czernik J. et al.: Wstępna ocena wyników le-
- czenia nerczaka wg schematu 01-92 Pol. Grupy Pediatrycznej leczenia Guzów Li-
- tych. Przegl. Ped., 1995, 25, Supl. 3, 257-262.
- 10. Tournade M.F., de KrakerJ., LemerleJ., Carli M., et al.: Preoperative chemotherapy
- of patients over 6 month of age with a nephroblastoma. A report of the SIOP Wilms
- Tumor Trials and Studies. Med. Ped. Oncol., 1994, 23, 171.
- 11. Tournade M.F., Com-Nougue C, Voute P.A., et al.: Results of 6th International So-
- ciety of Pediatric Oncology Wilms Tumor Trial and Study. J. Clin. Oncol., 1993, 11,
- 1014-20.
- 12. Zuppan C. W., Beckwith J.B., Weeks D.A., et al.: The effect of preoperative chemothe-
- rapy on the histologic features of Wilms tumor. Cancer 1991, 68, 385-394.
- 13. Delemarre F.M.: The new SIOP classification of renal tumor of childhood., Med.
- Ped. Oncol., 1996, 26, 145-146.
|