authors
-
Marek Sosnowski, Jacek Wilkosz, Marek Salagierski
- Klinika Urologii Instytutu Chirurgii AM w Łodzi
Kierownik Kliniki: prof. dr hab. med. L. Jeromin
keywords
-
testis neoplasms bilateral tumours
summary
- Objective. The aim of the study was retrospective analysis of the incidence,
- management methods and results of treatment of the patients with bilateral
- testicular tumours, .
- Material and methods. Among 239 patients treated for testicular tumours, in
- 7 (2,93%) tumours of the contralateral testis were also observed. A biopsy of
- the contralateral testis in 16 patients with risk factors led to the detection of
- carcinoma in situ (CIS) in 2 cases. 4 patients had identical histopathological
- findings in both testes - seminomas and a lymphoma, whereas in the remaining
- cases the types of tumours were different. Bilateral tumours were detected
- simultaneously in 3 patients, and in 6 remaining cases the interval between
- the diagnosis of the first and the second tumour ranged from 6 months to 6
- years (mean 33 months). The methods of treatment of the tumour in the first
- testis: radiotherapy, chemotherapy or retroperitoneal lymphadenectomy were
- instituted according to histopathological diagnosis and clinical stage of the
- disease. The tumours of the contralateral testis were treated using similar
- methods and taking into account the methods applied previously. CIS was
- treated without surgical castration, applying radiotherapy in one case and
- chemotherapy in the other. The patient with the lymphoma died 2 years after
- treatment and the remaining 6 ones survived during the period of follow-
- up, ranging from 1.5 to 16 years (mean 7.7 years).
- Conclusions. The authors present good results of treatment of bilateral germ
- cell tumours of the testes. Higher incidence of this disease in patients
- previously treated for germ cell tumours indicates the necessity of long-
- term follow-up and periodic control examinations of the contralateral testis.
- If Coincident risk factors are present, a control biopsy of the contralateral
- testis is recommended, which may lead to early detection of CIS and
- institution of effective conservative treatment.
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