NEPHRON-SPARING SURGERY
FOR RENAL CELL CARCINOMA
IN VON HIPPEL-LINDAU DISEASE
Article published in Urologia Polska 1998/51/2.
authors
-
Marcin Słojewski 1, Bartłomiej Gliniewicz 1, Andrzej Sikorski 1, Marek Grabowski 1, Karol Krzystolik 2, Cezary Cybulski 2, Jan Lubiński 2
- 1 Klinika Urologii PAM w Szczecinie
Kierownik Kliniki: prof. dr hab. med. A. Sikorski
2 Zakład Genetyki i Patomorfologii PAM w Szczecinie
Kierownik Zakładu: prof. dr hab. med. J. Lubiński
keywords
-
kidney kidney tumours nephron-sparing surgery
summary
- Objective. Von Hippel-Lindau disease is characterized by an inherited
- predisposition for tumour development. The most common manifestations
- in this syndrome are haemangioblastomas of the central nervous system,
- pancreatic cysts, pheochromocytomas, renal cysts and carcinomas. Almost
- 100% of solid renal tumours are renal cell carcinomas, very often bilateral
- and multifocal. It is proved that distant metastases of renal cancer in VHL
- patients with the primary lesion smaller than 3-5 cm in diameter do not occur.
- It justifies the decision of watchful waiting or renal sparing procedures.
- Materials and methods. We present our experience with 3 patients treated
- at our clinic for renal cell carcinoma in association with VHL diseas. In all
- cases nephron sparing surgery was performed. Oncological and functional
- results of treatment are good.
- Conclusions. Thorough follow-up of patients with VHL allows to initiate
- proper surgical treatment in an ade±uate moment. Local tumour excision is
- justified considering its common low grade, multifocal and recurrent character
- and good treatment outcomes.
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