authors
-
Wojciech Pawłowski 1, Edward Franek 2, Jan Myrta 1, Franciszek Kokot 2
- 1 Klinika Nefrologii ¦l. AM
Kierownik: prof. dr hab. n. med. F. Kokot
2 Oddział Urologii Szpitala Górniczego w Sosnowcu
Ordynator: dr n. med. J. Myrta
keywords
-
kidney kidney cysts gentamycine
summary
- Objective: The aim of the present study was to assess, the penetration of gentamicin
- into simple renal cysts. Patients and methods: To address this issue in 20 patients with
- simple renal cysts (14 of them had cysts of proximal origin and 6 of undetermined origin)
- 80 mg of gentamicin was given in single intravenous dosis 40 minutes before cyst punction.
- Simultaneously to the cyst punction blood sample was obtained from the cubital vein for
- assessment of serum gentamicin concentration. Cyst fluid and serum gentamicin
- concentrations were compared.
- Results: Serum gentamicin concentration in patients with simple renal cysts of proximal
- origin did not differ from the concentration in patients with cysts of undetermined origin
- 3, 66 ? 2, 27 vs. 5,2 ? 3,46 (?g/ml
- proximal cysts was lower than the concentration in cysts of undetermined origin
- 0,28?0,40 vs. 2,07?l,85 ?g/ml
- Conclusion: Results of the present study suggest that the penetration of gentamicin
- into proximal tubule-derived cysts is worse than into cysts of undetermined origin.
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