PTU - Polskie Towarzystwo Urologiczne
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DIAGNOSIS AND TREATMENT OF CARCINOMA IN SITU WITHIN CONTRALATERAL TESTIS OF MEN WITH UNILATERAL TESTICULAR GERMINAL CANCER
Article published in Urologia Polska 1997/50/1.

authors

Marek Sosnowski 1, Krzysztof Kula 2
1 Klinika Urologii Instytutu Chirurgii AM w Łodzi
Kierownik Kliniki: prof. dr hab. med. Leszek Jeromin
2 Pracownia Andrologii Klinicznej Instytutu Endokrynologii AM w Łodzi
Kierownik Pracowni Andrologii Klinicznej: prof. dr hab. med. K. Kula

keywords

testis ? tumours ? carcinoma in situ

summary

Objective. Fre±uency of the carcinoma in situ of the contralateral testis in patients
with testicular germinae cancer.
Patients and method. Surgical biopsies of the contralateral testis were performed in
15 men with unilateral testicular germinal cancer. In 12 cases testicular cancer was in
the Ist, and in 3 cases in the IInd clinical stage. Tissues were Bouin's fixed. In the paraffm
histological slides, a placental like alkaline phosphatase was immuno-histochemically
detecte, the enzyme that when is present within germinal cells of adult men, testicular
carcinoma in situ is diagnosed.
Results. CIS was found in 2 cases (13,3% of the whole examined patients): 1.
26 years old T.F. ? 3 years after hemicastration (TGC in the Ist stage); 2. 25
years old J.P. ? at the time of hemicastration (TGC in the IInd stage). In both
cases azoospermia was diagnosed before treatment. A repeated testicular biopses showed
disappearance of CIS after the following treatments: 1. T. R: radiotherapy, biopsy after
18th months ofthe completion, azoospermia; 2. J. R: Chemiotherapy, biopsy after 2 years
of the completion, followed by the appearance of spermatozoa in the ejaculate. These
introductory results suggest, that the fre±uency of the occurrence of CIS in the
contralateral testis of men with unilateral TGC, is high, and that the results of the
treatments of CIS are satisfactory.
Conclusion. The performence of testicular biopsy of contralateral testis, proper
histological diagnosis and treatment of CIS are highly indicated in TGC patients.

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