PTU - Polskie Towarzystwo Urologiczne
list of articles:

The significance of the stem cells in prostate cancer genesis and development
Article published in Urologia Polska 2005/58/3.

authors

Tomasz Drewa 1,2, Zbigniew Wolski 1, Dorota Olszewska-Słonina 2
(1Katedra i Klinika Urologii, Collegium Medicum im. L. Rydygiera w Bydgoszczy, Uniwersytet Mikołaja Kopernika w Toruniu
Kierownik kliniki: prof. dr hab. Zbigniew Wolski
2 Zakład Inżynierii Tkankowej, Katedra Biologii Medycznej, Collegium Medicum im. L. Rydygiera w Bydgoszczy, Uniwersytet Mikołaja Kopernika w Toruniu
Kierownik katedry: prof. dr hab. Gerard Drew

keywords

prostate, prostate cancer, stem cells, cell plasticity, transdifferentiation

summary

Introduction.
Stem cells can be found in all tissues, in the prostate epithelium as well. Stem cells are in focus of research of the cancer development and genesis, because they are multipotential and immortal.
The aim of the study.
The aim of the study was to present the prostate epithelial layer regeneration from self-renewal cells and possible connections of this process to prostate cancer genesis.
Material and methods.
In this issue types of stem cells and their origin were discussed. The structure of the prostate acinar model regeneration was described.
Conclusions.
Stem cells are crucial for generative layer of the prostate epithelium. The models explaining stem cells plasticity and differentiation can be associated with prostate cancer development.

references

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correspondence

Tomasz Drewa
ul. Karłowicza 24
85-094 Bydgoszcz
tomaszdrewa@wp.pl
www.tissue-engineering.webpark.pl