authors
-
Marek Pawlicki, Piotr Koralewski
- Z Kliniki Chemioterapii Oddziału Instytutu Onkologii w Krakowie
Kierownik Kliniki: doc. dr hab. med. M. Pawlicki Dyrektor Instytutu: doc. dr hab. med. J. Skołyszewski
summary
- In a group of patients with non-seminoma testicular tumours the effective-ness of palliative chemotherapy was analysed in relation to the microscopic pat-tern of the neoplasm, its progression grade and type of cytostatics. In patients with embryonal carcinoma 34.0°/o of remissions were obtained, in the teratoma group there were 13.0% remissions. The best results were obtained with drug combinations containing cisplatinum. The effects were poor in patients in poor general condition and with far advanced tumour.
references
- 1. Cavalli F., Olbjorn K., Hansen H. H., Alberto P.: EORTC Early Clinical Trials Group: A phase II study VP-16-213 in patients with non seminomatous testicular cancer Prac AARC/ASCO, 1980, 546. ? 2. Einhorn L. H., Donohue J. P.: Combination chemotherapy in disseminated testicular cancer: the India Univer-sity experience. Seminars in Oncology. 1979, 6, 87. ? 3. Einhorn L. U., Williams S. D.: Combination chemotherapy with cis-Dichlor diamine platinum and Adria-mycin for testicular cancer refractory to Vinblastin plus Bleomycin. Cancer Treat. Rep., 1978, 62, 1351. ? 4. Golbey R. B.: Germ cell cancer, w Clinical Interpreta-tion and Practice of Cancer E. M. Greenspan Raven Press, New York, 1982, 289. ? 5. Karnofsky D. A., Abelman W. H., Craver L., Burchenal I. H.: The use of nitrogen mustards in paliative treatment of carcinoma, Cancer. 1948, I. 634. ? 6. Ken-nedy B. J.: Mithramycin therapy in advanced testicular neoplasms. Cancer, 1970, 26, 755. ? 7. Miller A. B,, Hoogstraten B., Sta±uet M., Winklar A.: Repor-ting results of cancer treatment. Cancer, 1981, 47, 207. ? 8. Rejestr Nowotworów, Zakład Organizacji Walki z Rakiem i Epidemiologii Nowotworów Instytutu Onkologii im. Marii Sklodowskiej-Curie: Zachorowania i zgony na nowotwory zło¶liwe w Polsce i wybranych rejonach wiejskich w roku 1979, Warszawa, 1982. ? 9. Samuels M. L., Lanzotti V. J., Holyoke P. Y., Boyle L. E., Smith T. L., Johnson D. E.: Combination chemotherapy in germinal cell tumors. Cancer Treat. Rep., 1976, 3, 185. ? 10. Skolyszewski J.: Radioterapia Urologiczna, Instytut Fizyki J±drowej, Kraków, 1981, 63.
- 11. Williams S. D., Einhorn L. H., Greco F. A., Oldham R., Fletchar R.: VP--16-213: Salvage therapy for refractory germinal neoplasms, Cancer, 1980, 46, 2154. ? 12. Vugrin D., Civitkovic E., Whitmore W. F. Jr,. Cheng E., Goldberg R. B.: VAB--combination chemotherapy in treatment of metastatic testis tumors. Cancer, 1981, 47, 207.
|