USEFULNESS OF NUCLEAR MAGNETIC RESONANCE DETERMINATION (NMR) IN THE CLINICO-MORPHOLOGICAL EVALUATION OF PROSTATIC ADENOMA AND CARCINOMA
Article published in Urologia Polska 1986/39/3.

authors

Jan Szymanowski, Maciej Wysocki, Maria Barbara Gabryelewicz, Krzysztof Olszewski

Z Oddziału Urologicznego Szpitala Bielańskiego w Warszawie
Kierownik Oddziału: dr med, J. Szymanowski Z Zakładu Diagnostyki Patomorfologiczne: Centrum Medycznego
Kształcenia Podyplomowego w Warszawie
Kierownik Zakładu: prof. dr hab. med. M. Kobuszewska-Faryna Z Pracowni Radiospektrometrii Klinicznej Instytutu Położnictwa i Ginekologii
Akademii Medycznej w Poznaniu
Kierownik Pracowni: dr med. J. Bućko
Dyrektor Instytutu: prof. dr hab. med. T. Pisarski

summary

In 15 patients with the clinical diagnosis of prostatic adenoma or carcinoma 8 transurethral electroresections and 7 transvesical adenomectomies were per­formed.

In each case 4 fragments of prostatic tissue were taken for NMR examination determining the relaxation time T1 and T2 with a NMR impulse spectrometer operating at the freąuency of 27 MHz. The volume of the fragments was about 0,125 cm3. The study was done 24 hours after the operation. Microscopic exa-mination disclosed adono-carcinoma in 4 cases, prostatic adenoma in 10, and in 1 case atypical hyperplasia was found changing into mature malignant tumours.

It was conoluded that:

1.Seotions taken from neoplastic lesions show a significant prolongation of T2.

2.No significant prolongation of T1 was found in sections of prostatic car­

cinoma as compared with sections of prostatic adenoma.

3.Relaxation times T1 and T2 in the material obtained during transurethral

electroresection were significantly shorter than in tissues obtained during trans-

vesical adenomectomy.

references